Hahm, Bumsuk
Assistant Professor

The purpose of my research is to understand molecular and cellular mechanisms of how RNA viruses induce, evade, or suppress host immunity. We create and utilize small animal models for the infections with influenza virus, lymphocytic choriomeningitis virus and measles virus. We investigate dendritic cell response including type I interferon and toll-like receptor activation and T cell immunity upon RNA virus infections. Research projects include 1) Molecular dissection of measles virus-induced immunosuppression, 2) Immunotherapeutic approach to alleviate influenza viral immunopathology, and 3) STAT2-selective type I interferon signaling on dendritic cells. Our study should assist in the development of novel immunologic therapies to treat diseases caused by viral infection.