Pintel, David J.
Professor and Dr. R. Philip and Diane Acuff Professor in Medical Research

The parvoviruses are amongst the smallest of all viruses; they have a compact and highly regulated 5kb DNA genome and thus provide an excellent opportunity for understanding the life cycle of an important pathogen at a detailed molecular level, with the potential dividend of rational intervention in the disease process. In addition, since host cellular enzymes are involved in almost all biochemical functions involved in parvovirus replication, these viruses are excellent probes for gaining insight into basic mechanisms of eucaryotic cellular molecular biology.